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Introduction Sickle cell disease (SCD) is a genetic disorder that disproportionally affects people of African descent ( Intravascular hemolysis, a critical contributor to vaso-occlusive crises---the principal pathological manifestation of SCD---refers to the destruction of red blood cells (RBCs) within the blood vessels (Yusuf et al., 2010

Ferroptosis Iron-dependent form of cell death triggered by inactivation of cellular glutathione-dependent antioxidant defences with consequent accumulation of lipid reactive oxygen species

Starting carrier: Fluoranylmethoxycarbonyl Rink amide resin and other resins are used as starting carriers to provide a foundation for subsequent amino acid coupling

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