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It accelerates aging, impairs function, and lays the groundwork for chronic diseasesfrom heart issues to neurodegeneration

doi: 10.2147/vhrm.s9472

Obesity is a major cause of morbidity and mortality in children and adolescents with this syndrome via deterioration of the POMC-MC4R anorectic pathways [7, 8]

Patients with an EF 50% are defined as having heart failure with preserved ejection fraction (HFpEF) [1]

Who May Be a Better Candidate for Each Approach Standard titration may be a fit for those who tolerate the GI side effects reasonably well, want to reach therapeutic doses efficiently, and are following a structured program with regular provider check-ins