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(average results) Wegovy (semaglutide) GLP-1 only In the STEP-1 study (68 weeks), average weight change was about: 14.9% with Wegovy 2.4% with placebo (dummy injection) What that looks like: If you start at 100 kg , 14.9% is about 15 kg lost on average

And theyre very expensive: with out-of-pocket prices averaging $1000 to $1500 a month, theyre unaffordable for most people

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A summary of genomic studies related to depression is presented in Table 1