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Companies locating there "took advantage of advancements in building construction and were able to encompass even larger amounts of space dedicated entirely to the production of tobacco products, primarily cigarettes"

a Levels in all products except for e-cigarette liquids are expressed as mg/g of product (converted from % weight-based data in some reports)

MichaelisMenten transport kinetics of human NTCP wild type (circle)- and Q261A mutant (triangle)-mediated [ 3 H]-TCA uptake

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The decrease in the practice of indentured servitude after 1676 CE, and the intense labor required for tobacco crops, led to the increase in importing African slaves and enslaving Native Americans