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ReShape Lifesciences (RSLS) noted that GLP-1s have reduced initial consultations for its LAP-BAND Surgery. LastBearStanding on Substack Teleflex Incorporated, Q2 2023 Earnings Call, Aug 03, 2023: We continue to monitor the usage of GLP-1 drugs in treating obesity

10.1016/s0140-6736(20)32205-4 Lancet 54 SchererT.SakamotoK.BuettnerC

Mitochondrial dysfunction

Of that, ~60% was from fat mass and 40% was from lean body mass

These alterations in metabolic pathways and metabolites can fulfill bio-energetic requirements, promote cell proliferation, drive inflammatory mediator secretion, mediate leukocyte infiltration, induce joint destruction and muscle atrophy, and regulate cell proliferation, which may reflect the etiologies of RA