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SGLT2 inhibitors promote ketogenesis, increasing circulating -hydroxybutyrate (BHB), which serves as an alternative energy source and reduces oxidative stress and systemic inflammation [18, 40]

Plaintiffs allege that these manufacturers failed to adequately warn about severe gastrointestinal risks, including gastroparesis, ileus, intestinal obstruction, pseudo-obstruction, and related injuries

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Food Funct 2020;11:792534 [DOI] [PubMed] [Google Scholar] 53.Imaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, Flavell RA, Mehal WZ.Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome