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Research focuses on metabolic function, insulin sensitivity, and cellular energy production
The case for stacking them rests on a single observation: the four receptor systems involved GLP-1, GIP, glucagon, and amylin are all non-overlapping
It is chemically a true peptide (six amino acids, including two D-amino acid substitutions for stability), so unlike some non-peptide GH secretagogues it is correctly classified in this category
However, in some cases, rare side effects may be observed such as nausea, diarrhea, anorexia and rash
After activation, they influence metabolic gene expression and interact with coactivator networks that include PGC-1 and PGC-1
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