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Similarly, hippurate, a normal excretory product of urine that is increased with exposure to phenolic compounds and toluene, a byproduct of cigarette smoke 73 , was increased in Lactobacillus -dominated CST-I/III over CST-IV and also in non-smokers over smokers

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In the absence of large controlled studies in comorbid BD and TUD or ND, pharmacological treatment follows the individual guidance for each disorder