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Therefore, compounds that influence the functions of these efflux pumps may be a promising target for antibiotic potentiation
These findings support the concept that the microbiota indirectly modulates -cell subpopulations through the adipose tissueinflammationinsulin resistance and SCFA/LPSincretins-cells axes, even though direct single-cell studies demonstrating differential responses of individual -cell subtypes to microbiota-derived metabolites are not yet available ( via the MyD88 or TRIF adaptors, leading to NF-B activation and induction of pro-inflammatory genes encoding IL-1, IL-6, and TNF- (Lumeng, 2013)
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In preclinical research it is studied for its reported effects on tissue repair including tendon, ligament, muscle, and gut-lining models
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