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Many people labelled as non-responders to GLP-1 receptor agonists such as semaglutide do not take the medication correctly or discontinue treatment before adequate therapeutic effect can be achieved

The standard titration for Ozempic begins at 0.25 mg weekly for four weeks, increasing to 0.5 mg weekly, with potential further increases to 1 mg or 2 mg based on glycemic response and tolerability

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