Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, et al
Vitamin B12 is an essential nutrient involved in red blood cell formation, neurological function, DNA synthesis, and cellular energy metabolism
In addition, berberine can induce activation of PI3K/AKT signaling pathway, which is related to Nrf2 expression and neuroprotection (Zhang et al., 2017)
These mechanistic insights have led to the exploration of NOX isoform-specific inhibition as a promising therapeutic approach to mitigate pathological ECM remodeling in fibrotic diseases
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