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Additionally, acteoside, a major active compound, has been reported to alleviate renal fibrosis and glycolipid metabolic disturbances by reducing oxidative stress and inflammation in -cells, modulating the unfolded protein response, improving mitochondrial dynamics, and enhancing -cell function and insulin secretion (69)
Tang H, Donahoo WT, Svensson M, Shaaban CE, Smith G, Jaffee MS, et al
When things go right, Shed communication is praised
Drugging this type of GPCR with small molecules has its challenges say Jeff Finer, chief executive of Septerna, a biotech based in south San Francisco, US
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