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Control of cellular serine metabolism by NRF2 supports proliferation and antioxidant defense Suppression of ROS is not the only mechanism by which NRF2 influences tumorigenesis

Cell types also differ in their biotransforming potential for example cells located near the major points of xenobiotic entry into the body such as liver, lung, and intestine possess greater concentrations of biotransforming enzymes than others [52]

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Its also consistent with the tendency of full-blown SLOS patients toward self-injurious behavior

M., Liu, Y., Crosson, C