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Chen S, Zhou M, Sun J, Guo A, Fernando RL, Chen Y et al (2019) DPP-4 inhibitor improves learning and memory deficits and AD-like neurodegeneration by modulating the GLP-1 signaling

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Early satiety from GLP-1 medications is described as feeling comfortably full after eating much smaller portions than usual, often accompanied by reduced interest in food and decreased cravings

In addition, the isoprenyl group can react with cysteine thiol and bind to proteins, thus forming irreversible S -prenylation reactions such as farnesylation

Ongoing clinical trials continue to investigate the long-term neurological effects of GLP-1 receptor agonists, and future research may provide further clarity on their role in cognitive health