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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

Retrieved May 12, 2025, from Nguyen, M., & Tadi, P

Although animal models provide a more integrated physiological context, their translational value is limited by interspecies differences in copper metabolism and the difficulty in modelling human-specific gene-environment interactions [253]

[26] If your nausea is particularly severe, your doctor may prescribe metoclopramide (Reglan)

These behavioral and neurochemical changes underlie alcohols rewarding properties and contribute to the risk of developing AUD (5-8)