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The Mayo Clinic emphasizes that effective weight loss medications require regulatory oversight and clinical validation

Ensure any provider is properly regulated: Pharmacies should be registered with the General Pharmaceutical Council (GPhC) Prescribers must be GMC-registered Clinics should be registered with the Care Quality Commission (CQC) Be extremely cautious of unregulated sources

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2020;105(4):dgaa061

If cholelithiasis is suspected, gallbladder studies and appropriate clinical follow-up are indicated." [3] Patients with prior gallbladder disease, obesity-related fatty liver disease, or a personal or family history of gallstones should discuss gallbladder monitoring with their prescriber before starting a GLP-1 agent