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While semaglutide works by activating the GLP-1 receptor, retatrutide activates GLP-1, GIP, and GCG receptors, which may offer even more benefits

It is not clear whether this is due to the drugs themselves or the weight loss that they cause

The medication should be avoided during pregnancy and discontinued at least 2 months before a planned pregnancy

The injectable drug, initially only used as diabetes medication, is the first drug since Saxenda (2014) approved to treat chronic weight management in the 70% of American adults who are obese or overweight

These injections go right beneath the skin (rather than into the muscle)