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All the internal connections are made of conventional hydrogen bond type that will guarantee its adaptability and strength since it shaped by triple amino acids (cysteine, glutamic acid, and glycine) appended through peptide linkage and as of now introduced in the active site which increases the reactivity and viability, this factor favorites covalently the fixation of glutathione

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When TPIAT was first implemented to treat CP several decades ago, the outcomes were variable owing to the lack of standards for islet isolation

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