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A recent study suggests that GLP-1 medications, commonly prescribed for managing diabetes and obesity, may also lower the risk of dangerous blood clots

Funding: This work was supported by National Natural Science Foundation of China (Grant No#: 81471026, to A.W.) and Diabetes Doctors Foundation of China (to A.W.)

Together, our results suggest that exendin-4 induces adiponectin expression through the Sirt1/Foxo-1 signaling, and Foxo-1 functions as a transcription factor mediating the effect of exendin-4 on adiponectin expression

62 A number of our results, in both AP and CP models, are consistent with the conclusion that GLP-1Rs are expressed in activated PSCs and expression is increased over normal pancreas

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