[DOI] [PubMed] [Google Scholar] 28.Watanabe S., Ajisaka R., Masuoka T., Yamanouchi T., Saitou T., Toyama M., Takeyasu N., Sakamoto K., Sugishita Y
Retatrutide, development code LY3437943, is Eli Lilly's investigational triple hormone receptor agonist
Determination of protein concentration in supernatant using BCA protein Assay Kit (Applygen Technologies, Beijing, China), and equal amounts of total protein underwent 10% SDS-PAGE and were transferred to polyvinylidene difluoride membranes, which were blocked with 5% non-fat milk, and incubated with different primary antibodies overnight at 4 C
Animal studies and small clinical trials indicate possible mechanisms, but no large rigorous trials exist to confirm safety and efficacy for fertility
Results: In total, n=679 individuals were included, 49.8% women, mean age of 47.810.7 years, T1D duration of 26.910.8 years, mean body mass index 26.14.3 kg/m2 (15.9% with obesity)