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The in vitro test battery comprising assays for bacterial mutagenicity, mammalian cytogenetics/mutation, and mammalian cytotoxicity, that has been suggested by a CORESTA task force in 2004 ( in vitro tests can specifically address smoking related adverse effects, as biphasic culture of airway epithelial cells or assays on endothelial activation as conducted by the manufacturers ( in vitro cultured lungs tissues are now available by several commercial suppliers

[PubMed: 7781690] Eaker DW

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