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Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects (Sansgiry et al., 2017)

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However, excess sebum production can lead to clogged pores and inflammation, resulting in acne

Briefly, the Plugin segments individual nuclei, filters them by size, excludes nuclei touching the edges of the field of view, segments single cells using background subtraction and seeded watershed segmentation, and detects lysosomes using the Laplacian of Gauss (LoG) filter and the Find Maxima command