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Metabolic intermediates for biosynthesis Despite the original idea of Warburg [2] that aerobic glycolysis was originated as a consequence of mitochondrial dysfunction, subsequent studies showed that mitochondria of cancer cells are still functional and able to conduct oxidative phosphorylation

It is generally accepted that NT-proBNP levels are biochemical markers of the extent of cardiac damage and predictors of adverse outcomes

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To help overcome this limitation, our work focused on integrating data from multiple sources, including genetics, as well as complex signatures rather than individual proteins