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The FDA initiated the review in mid-2023 after reports surfaced of suicidal ideation among some individuals using GLP-1 medications for weight loss

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Similar to rapamycin 31 , these effects were achieved even though not initiated until later in life, which we reasoned to be a safer therapeutic window for IGF-1R modulation than younger ages 34

While research on Dihexa is promising, it is important to note that most studies have been conducted in animals or in vitro

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