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Clinicians should consider several potential concerns during evaluation: Unknown active ingredient source Variable potency or concentration Differences in excipients Sterility concerns for injectable products Dosing inaccuracies Limited stability data Inconsistent patient instructions The FDA has also warned healthcare professionals about compounded products made with salt forms of semaglutide that differ from the approved active ingredient

Its action is confined to fat tissue

With semaglutide , common side effects include: Nausea Vomiting Diarrhea Constipation Abdominal pain Read more: Semaglutide side effects: Symptom guide & management tips With retatrutide , early clinical trials show a very similar pattern so far, including: Nausea (often the most reported) Diarrhea Constipation Vomiting Lets take a look at how some of those most common side effects compare between semaglutide (Wegovy 2.4 mg and 7.2 mg) and retatrutide

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Although typically well tolerated without food, some people experience digestive discomfort and diarrhea when taking larger amounts