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In addition, activation of GLP-1R regulates mitochondrial over fission by the cAMP/PKA pathway while improving mitochondrial function in A-treated astrocytes and ameliorating pathological lesions in AD (Xie et al., 2021)

This contrasts with the successful management of PWS [3, 15] and emphasizes that effective multidisciplinary care must be adaptable to families socioeconomic realities