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The study focused in particular on the dose-dependent effects of smoking behaviour on the occurrence of depression

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Figure 1 For nearly as long as we have recognized PD, epidemiologic studies have suggested that extrinsic factors, including increasing age, male sex, environmental agent exposure, such as pesticide and chlorinated solvents exposure, unhealthy lifestyle, such as high dietary intake of dairy products, lower socioeconomic status, rural living, and traumatic brain injury (TBI), as well as intrinsic factors, including genetic predisposition, unusual metabolic states, and comorbidities such as diabetes, can be recognized as risk factors (Ben-Shlomo et al., 2024

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