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Neuron 28 , 727740 (2000)

The problem is that the digestive process, particularly stomach acid and the enzyme gamma-glutamyltransferase present in the gut lumen, can cleave glutathione into its constituent amino acids (glutamate, cysteine, glycine) before it is absorbed intact

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It is important to note that Glutathione IV therapy should be used under the guidance of a healthcare professional