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Description

Rapamycin treatment for amyotrophic lateral sclerosis: Protocol for a phase II randomized, double-blind, placebo-controlled, multicenter, clinical trial (RAP-ALS trial)

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Hepatic encephalopathy, as a consequence of advanced liver disease, is the major manifestation of the perturbed brain-gut microbiome axis

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Loss of proteostasis : This is a loss of protein homeostasis due to misfolded proteinsold proteins [at the cellular level]

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Bae M, Cassilly CD, Liu X, et al

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GSH depletion sets the stage for ferroptosis induction in hepatocellular carcinoma cells [214]

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