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The lowest available pen dose for semaglutide (brand name Ozempic for diabetes, Wegovy for obesity) is 0.25 mg

GLP-1 RAs exert immunomodulatory properties through peripheral and central pathways

At the highest dose tested, participants in the retatrutide group achieved mean body weight reductions of approximately 24% a figure that exceeded results previously reported for single-agonist (semaglutide) and dual-agonist (tirzepatide) compounds at comparable trial stages

Controlled drugs are delivered using a specialist courier service to ensure secure and compliant handling in accordance with UK regulations

Nature 404 , 661671 (2000)