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Brain-derived neurotrophic factor (BDNF) is important for neurogenesis, and various depressive symptoms arise from decreased BDNF levels (Sahay and Hen, 2007)

The most practical approach is baseline screening, symptom tracking, careful follow-up, and early communication when mood changes appear

This array could include GH proteins (recGH and pitGH) , GH biomarkers (IGF-I, P-III-NP) and potential new biomarkers: fibronectin1 (FN1) and apolipoprotein 1 (APOL1) and Vitamin D binding protein (VDBP)

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Semaglutide was first approved by the US Food and Drug Administration (FDA) as Ozempic for the treatment of type 2 diabetes back in 2017