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95 Future studies need to combine single-cell transcriptomics and ubiquitin-modified omics to analyze the dynamic regulatory network of the proteasome, UPS and ALP during aging to ensure the correct synthesis, folding, and degradation of proteins, effectively ameliorating age-related pathologies

For example, Chauhan et al

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Vegetarians, vegans, and individuals over 50 are particularly susceptible to B12 deficiency because it is mainly found in animal products, and the bodys ability to absorb it decreases with age

Analysis of clinical data clearly demonstrates that mitochondrial dysfunction accompanies disease progression in a substantial proportion of patients