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It is also based on the arginine paradox, discussed above, that despite an intracellular L-arginine concentration much higher than its K m for eNOS activity, high extracellular concentration of L-arginine can still promote NO production

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Using the Broad Institutes Connectivity Map, the group reported that GHK modulates the expression of a very large number of human genes, on the order of thousands, and tends to shift pathological or aged expression patterns back toward a healthier, younger profile

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Dennis Kelly This is not something that produces immediate or dramatic results