doi: 10.1093/annonc/mdz158
Carnitine is, thus, essential for transferring long-chain fatty acids to the mitochondrial matrix and subsequently promotes energy metabolism and adenosine triphosphate production by activating the -oxidation of fatty acids [3]
Similarly, no significant differences in triglyceride concentrations were detected in 12-week-old male and female C57BL/6J offspring following maternal GLU or FRU diets, although a slight reduction was again noted [40]
Khrunin et al showed that 104 patients with ovarian cancer with mutant-type GST possessed longer progression-free survival compared to wild-type GST
Gradual dose escalation is crucial for mitigating AEs, while combination with other medications, including oral antidiabetic agents, and consideration of polypharmacy in older adults, as well as individualization of therapy, should consider comorbidities, gastrointestinal tolerability, and cost