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Even if the solution appears clear, peptide bond hydrolysis and oxidation have likely reduced bioavailability by 1530%, compromising experimental consistency

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For example, IF has been shown in overweight and obese human subjects during Ramadan to modulate expression of SIRT1, SIRT3, and antioxidant genes, though results are mixed and often depend on gene expression rather than direct functional assays [38]

10.1002/mc.22124 Mol