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Result Confirmed the Phase 2 efficacy pattern: significant weight loss at both 0.25 mg and 0.5 mg compared to placebo, with about 10% mean weight loss at the higher dose over 24 weeks

This leads to a buildup of acetaldehyde in the body, which is what triggers the facial flushing, rapid heartbeat, and other uncomfortable symptoms of alcohol flush reaction

It is a carnitine specific transporter that disappeared during evolution: it is present in mouse, but not in chimpanzee or humans (Pochini et al., 2013)

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At 12, 24, and 36 months, the T2D remission rates were 88.2%, 82.4%, and 88.2% in the No-GLP-1 group, and 85.0%, 85.0%, and 90.0% in the GLP-1 group, respectively