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Choline: an essential nutrient for humans

Inactivation of GPX4 can occur in the presence of the inhibitor Ras-selective Lethal 3 (RSL3) or by binding to cisplatin, leading to the accumulation of ROS and ultimately promoting ferroptosis [67]

The respiratory explosion generates the catalytic conversion of the molecular oxygen in the super oxide anion that leads to the hydrogen peroxide formation, the hypochlorous acid and the hydroxile radicals