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The study reveals that the SLC25A39 transporter, which imports glutathione into mitochondria, is essential for cancer spread, and elevated SLC25A39 expression correlates with poorer survival outcomes in breast cancer patients, suggesting potential therapeutic targeting opportunities
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The findings indicated that metformin treatment led to enhanced endometrial tolerance through the downregulation of tolerance-related miRNAs, specifically miR-1910-3p and miR-491-3p, resulting in elevated expression of endometrial tolerance markers HOXA10 and ITGB3 in patients with PCOS
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