Interestingly, a study in 2003 showed that those who underwent coronary angiography and died of heart attacks had much lower glutathione peroxidase than those who survived (8)
The careful answer is that they may support collagen, elastin, repair signaling, and inflammation control, but topical anti-aging trials are much thinner than the marketing often implies [1][2]
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This includes upregulating genes responsible for critical processes such as collagen and elastin synthesis, angiogenesis, and antioxidant production
Additionally, vascular dysfunction, endothelial dysfunction, and microclot presence may also promote vasoconstriction and tissue hypoxia