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It also does not establish pharmacological safety, human bioavailability or clinical effectiveness

Link to Study Resources: Lojo, N., Medvidovic-Grubisic, M., & Drmic, D

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For instance, the development of autoimmune diseases is stimulated by iodine (excess or deficiency), smoking, stress, and chemical contaminants (like polyaromatic hydrocarbons), medicine (like amiodarone and interferon-alpha (IFN), and bacterial and viral infections (like hepatitis C virus and Yersinia enterocolitica)