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Surgical management is indicated for patients with BMI 35 kg/m 2 with 1 obesity-related complication or BMI 40 kg/m 2 , even though less than 2% of eligible patients actually receive this treatment 9

Validating non-invasive biomarkers (e.g., urine exosomal ferroptosis-related proteins and circulating lipid peroxide metabolites) that reflect renal ferroptosis activity in CKD patients with RF is urgently needed for early diagnosis and therapeutic monitoring

By enhancing satiety and reducing appetite, patients may experience a decrease in overall caloric intake

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Additionally, an imbalance in the w-6:w-3 ratios is associated with maternal postpartum depression (PPD), suggesting that addressing the competition between w-3 and w-6 could be a therapeutic approach for treating depression (320)