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In any case, we think that the observed effect reflects a mechanism of action inherent to targeting the GLP-1 receptor. Braca said they decided to study the potential impact of GLP-1s on migraine based on previous work done by their research team, which suspected that a derangement in intracranial pressure control plays a role in the pathophysiology of migraine

The area ratio values obtained from the analysis were normalized using statTarget and internal standard correction

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doi:10.1016/j.cmet.2013.04.008 2