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Smoking markedly augments thrombotic risk with systemic estrogen, and maintaining routine exercise, a balanced diet, and regular blood-pressure checks may help lower cardiovascular complications

The data indicated that 0.5mg and 1mg/weekly semaglutide reduced the risk of experiencing death from cardiovascular causes by 26% and the risk of nonfatal stroke by 39% compared to placebo [22]

GLP-1 medications such as semaglutide are not used during pregnancy, in people with a personal or family history of medullary thyroid carcinoma or MEN 2, or in patients with active pancreatitis, and they are not prescribed to children under 12

Raftos JE, Whillier S, Kuchel PW