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Dose Escalation Protocols and Managing Dose Interruptions The HealthRX clinical team uses a structured three-tier decision tree when a patient reports adverse events during GLP-1 up-titration: Tier 1 (Grade 1 GI, no functional impairment): Continue current dose

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If you experience severe pain during injection, stop immediately and try a different site with adequate subcutaneous thickness, typically the abdomen or outer thigh

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