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It was found that small colony variants of Staphylococcus aureus compromise host immunity by activating host cell glycolysis to induce necroptosis (182)

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Emerging evidence further indicates that MTs particularly MT1 and MT2A constitute a critical cytoplasmic defense layer against cuproptosis by acting as effective copper sponges that sequester excess Cu + and restrict its aberrant interaction with mitochondrial targets 170,173,174