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SKU: 88678502045

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Zhang M, Han W, Hu S, Xu H

By remaining open to all therapeutic possibilities whether they're natural compounds, lifestyle interventions, or repurposed pharmaceuticals we can offer our patients the most comprehensive and effective care possible

USA 93 , 1503615040 (1996)

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We report the identification of clofibric acid as a ligand for the E3 ubiquitin ligase synoviolin (SYVN1) and demonstrate its use in designing SYVN1-recruiting PROTACs that drive selective degradation of BRD4